Online First

June 15, 2021

June 10, 2021

June 09, 2021

  • Original research
    Aqueous chlorhexidine 1% versus 2% for neonatal skin antisepsis: a randomised non-inferiority trial
    Akash Sharma, Srikant Kulkarni, Anu Thukral, M Jeeva Sankar, Ramesh Agarwal, A K Deorari, Sarita Mohapatra, Thirumurthy Velpandian, Minu Bajpai

    This controlled trial tested different strengths of aqueous chlorhexidine for neonatal skin antisepsis prior to intravenous cannulation in a neonatal intensive care unit in India, finding that 1% chlorhexidine was effective, but not clearly equivalent to 2% which pending further research remains the recommended concentration for this purpose.

  • Original research
    Effect of breathing on venous return during delayed cord clamping: an observational study
    Emma Brouwer, Ronny Knol, Annie Kroushev, Thomas Van Den Akker, Stuart B Hooper, Arno A Roest, Arjan B te Pas

    Real-time echocardiographic monitoring of blood flow in the ductus venosus and hepatic vein was undertaken during perinatal transition with intact umbilical cord of term born infants. Antegrade flow increased during inspiration, preferentially directing blood flow from the ductus venosus into the right atrium.

June 03, 2021

May 27, 2021

May 26, 2021

May 21, 2021

  • Original research
    Neuronal exosome proteins: novel biomarkers for predicting neonatal response to therapeutic hypothermia
    Beth Pineles, Arunmani Mani, Livia Sura, Candace Rossignol, Mehmet Albayram, Michael David Weiss, Laura Goetzl

    In an observational cohort study, exosome based central nervous system biomarkers from peripheral blood in newborns less than 12 hours old undergoing hypothermia for hypoxic-ischemic encephalopathy differentiated those with favorable and unfavorable MRI injury scores at 5-7 days.

May 20, 2021

May 14, 2021

  • Original research
    Early lung ultrasound affords little to the prediction of bronchopulmonary dysplasia
    Patricia Lee Woods, Benjamin Stoecklin, Amanda Woods, Andrew William Gill

    These investigators report a prospective analysis of preterm babies < 28 weeks gestation in whom lung ultrasounds were performed on a scheduled basis. They found that u/s was predictive in univariate analysis of the development of BPD, but added little to the predictive value when gestational age was included in the model.

  • Original research
    Neonatal arterial stroke location is associated with outcome at 2 years: a voxel-based lesion-symptom mapping study
    Christian Núñez, Christian Stephan-Otto, Gemma Arca, Thais Agut, Juan Arnaez, Malaika Cordeiro, Isabel Benavente-Fernández, Nuria Boronat, Simón Pedro Lubián-López, Eva Valverde, Montesclaros Hortigüela, Alfredo García-Alix

    In a prospective observational multicenter study of neonatal stroke, lesion location identified by MRI is associated with language, motor, and cognitive outcomes at two years of age.

  • Short report
    Nasal expression of SARS-CoV-2 entry receptors in newborns
    Santtu Heinonen, Otto Helve, Sture Andersson, Cecilia Janér, Liina Süvari, Anu Kaskinen

    Low nasal expression of SARS-CoV-2 entry receptors in newborns in both preterm and term cases may contribute to the low attack rates and mild disease in newborns.

May 10, 2021

May 07, 2021

  • Original research
    Automated control of oxygen titration in preterm infants on non-invasive respiratory support
    Peter A Dargaville, Andrew P Marshall, Oliver J Ladlow, Charlotte Bannink, Rohan Jayakar, Caillin Eastwood-Sutherland, Kathleen Lim, Sanoj K M Ali, Timothy J Gale

    An automated oxygen controller increased the proportion of time that oxygen dependent preterm infants on non-invasive respiratory support spent in their target SpO2 range and reduced their exposure to extremes of SpO2.

  • Short report
    Prospective comparison of thermometers used in very preterm infants
    Emma A Dunne, Colm Patrick Finbarr O'Donnell, Lisa K McCarthy

    When used in predictive mode an electronic thermometer performed poorly for detecting hypothermia on admission to the neonatal unit.

May 06, 2021

  • Original research
    Intrapartum group B Streptococcal prophylaxis and childhood weight gain
    Sagori Mukhopadhyay, Matthew Bryan, Miren B Dhudasia, William Quarshie, Jeffrey S Gerber, Robert W Grundmeier, Corinna Koebnick, Margo A Sidell, Darios Getahun, Andrea J Sharma, Michael W Spiller, Stephanie J Schrag, Karen Marie Puopolo

    Retrospective study of a large cohort of term babies followed up for 5 years. Just under a fifth (17%) of these babies were exposed to antibiotics given to the mother for GBS prophylaxis and these had elevated weight gain in the first 5 yrs. The authors suggest alteration of microbiome as a possible mechanism.

May 05, 2021

April 30, 2021

April 29, 2021

April 27, 2021

April 21, 2021

  • Review
    Safe emergency neonatal airway management: current challenges and potential approaches
    Joyce E O'Shea, Alexandra Scrivens, Gemma Edwards, Charles Christoph Roehr

    This review describes the challenges encountered with neonatal intubation, particularly in relation to training and achieving competency. It discusses strategies to optimise intubation success and examines the airway adjuncts currently available to manage the neonatal airway.

April 20, 2021

April 13, 2021

March 31, 2021

  • Original research
    Osteopathic manipulative treatment to improve exclusive breast feeding at 1 month
    Marie Danielo Jouhier, Cécile Boscher, Jean-Christophe Roze, Nicolas Cailleau, Frédéric Chaligne, Arnaud Legrand, Cyril Flamant, Jean-Baptiste Muller NEOSTEO osteopath study group

    This single centre RCT of 128 mother/infant dyads experiencing breast feeding difficulties showed that early osteopathic manipulative treatment did not improve exclusive breast-feeding rates at one month.

March 11, 2021

  • Original research
    Thermal management with and without servo-controlled system in preterm infants immediately after birth: a multicentre, randomised controlled study
    Francesco Cavallin, Nicoletta Doglioni, Alessandra Allodi, Nadia Battajon, Stefania Vedovato, Letizia Capasso, Eloisa Gitto, Nicola Laforgia, Giulia Paviotti, Maria Grazia Capretti, Camilla Gizzi, Paolo Ernesto Villani, Paolo Biban, Simone Pratesi, Gianluca Lista, Fabrizio Ciralli, Massimo Soffiati, Alex Staffler, Eugenio Baraldi, Daniele Trevisanuto on behalf of Servo COntrol for PReterm Infants (SCOPRI) Trial Group

    This multicentre double blind RCT of 450 preterm infants evaluated the effectiveness of a thermal servo-controlled system in the delivery room. There was no important difference in rates of normothermia but the servo-controlled system was associated with increased mild hypothermia.

March 09, 2021

  • Original research
    Randomised trial of epinephrine dose and flush volume in term newborn lambs
    Deepika Sankaran, Praveen K Chandrasekharan, Sylvia F Gugino, Carmon Koenigsknecht, Justin Helman, Jayasree Nair, Bobby Mathew, Munmun Rawat, Payam Vali, Lori Nielsen, Daniel J Tancredi, Satyan Lakshminrusimha

    In newborn lambs with cardiac arrest, higher doses of adrenaline and larger flush volumes were more effective in achieving return of spontaneous circulation during cardiopulmonary resuscitation.

March 03, 2021

February 24, 2021

February 17, 2021

February 10, 2021

  • Letter
    Follow-up after very preterm birth in Europe
    Anna-Veera Seppänen, Elizabeth S Draper, Stavros Petrou, Henrique Barros, Lazaros Andronis, Sung Wook Kim, Rolf F Maier, Pernille Pedersen, Janusz Gadzinowski, Jo Lebeer, Ulrika Ådén, Liis Toome, Arno F J van Heijst, Marina Cuttini, Jennifer Zeitlin SHIPS Research Group
  • Images in neonatal medicine
    Ecthyma gangrenosum in a premature infant: rare but critical to recognise
    Merle Caron, Claudy Oliveira dos Santos, Marieke Anne Catharine Hemels, Esther J d'Haens

February 04, 2021

January 29, 2021

January 25, 2021