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November 07, 2022
- Original researchNasal high-flow therapy to Optimise Stability during Intubation: the NOSI pilot trial
Pilot study investigating the feasibility of blinding the use of high-flow nasal cannula oxygen during neonatal intubation and showing no effect on the proportion of time spent in hypoxemia.
November 03, 2022
October 28, 2022
October 21, 2022
- Original researchChange in neurodevelopmental outcomes for extremely premature infants over time: a systematic review and meta-analysis
In a systematic review and meta-analysis, there was no significant change in neurodevelopmental impairment rates reported between 1990 and 2020 when comparing same-center cohorts. This finding points to need for family-focused and brain health interventions to improve outcomes.
October 19, 2022
- Original researchDo newborn infants exhale through the CPAP system? Secondary analysis of a randomised cross-over trial
In this study, investigators demonstrate for the first time that newborns receiving low levels of CPAP pressure are able to exhale through the CPAP circuit.
- Original researchPredicting the likelihood of lower respiratory tract Ureaplasma infection in preterms
Predictive models to determine the likelihood of lower respiratory tract Ureaplasma infection were developed based on perinatal clinical information available.These models may be useful in the design of clinical trials of therapeutic interventions to prevent Ureaplasma-mediated BPD.
October 17, 2022
- Original researchExposure to umbilical cord management approaches and death or neurodevelopmental impairment at 22–26 months’ corrected age after extremely preterm birth
This retrospective study followed 1900 infants born < 27 weeks’ gestation to two years’ corrected age. Infants undergoing delayed cord clamping had lower rates of death or severe neurodevelopmental impairment. The effect was not mediated by severe intraventicular haemorrhage.
October 12, 2022
- Original researchDiaphragm electrical activity during weaning of nasal high-flow therapy in preterm infants
Investigators in this manuscript examined electrical activity of the diaphragm (Edi) in 40 preterm infants during pre-specified weaning of high flow nasal cannula. Edi significantly increased only after the final wean from 2L/min of flow, suggesting increased work of breathing.