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Extensive aplasia cutis congenita of the trunk
  1. Alexander Höttler1,
  2. Stephan Forchhammer2,
  3. Thomas Mentzel3,
  4. Karen Birgit Kreutzer1,
  5. Cornelia Wiechers1,
  6. Alexander Scheu2
  1. 1 Department of Neonatology, University Hospital Tübingen, Tübingen, Germany
  2. 2 Department of Dermatology, University Hospital Tübingen, Tübingen, Germany
  3. 3 MVZ Dermatopathology, Friedrichshafen, Germany
  1. Correspondence to Dr Alexander Höttler; alexander.hoettler{at}med.uni-tuebingen.de

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A female newborn of non-consanguineous parents, delivered at term via caesarean section, presented with a sharply bordered ulceration reaching from the left parasternal line to the left posterior axillary line (figure 1A).

Figure 1

(A) Photo on day 1 of life: The lesion was fibrin-coated in the center, necrotic at the margins with livid discoloration of surrounding skin parts, mobile and non-tender. (B) Photo after 8 months under conservative treatment. (C) Hematoxylin and eosin stain of the biopsy from the margin of the ulcer showing deep tissue necrosis and reactive blood-vessel proliferation with fibrosis and hemosiderin …

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Footnotes

  • Contributors AH conceived the idea for the article, performed literature search, drafted the original manuscript, managed the case, took relevant clinical pictures and was responsible for the overall content. AS primarily managed the case and the follow-up, took relevant clinical pictures and revised the manuscript. SF performed the histological analysis, provided the histological picture and revised the manuscript. TM contributed additional histological analysis and revised the manuscript. KBK managed the case and revised the manuscript. CW supervised the case and revised the manuscript. All authors reviewed and agreed with the final version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.