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Catheter insertion depths in less-invasive surfactant administration


Introduction Less-invasive surfactant administration (LISA) under continuous positive airway pressure is increasingly used for the treatment of neonatal respiratory distress. Different procedures are described, but data on the optimal catheter insertion depth are sparse.

Objective To generate data for recommending an optimal catheter insertion depth in LISA.

Methods We examined 112 anterior–posterior chest X-rays from intubated infants and determined the carina’s vertebral projection, whenever possible. After that, distances between the middle of cervical vertebra 4 (C4) and thoracic vertebra 2 and the middle of C4 to thoracic vertebra 3, respectively, were measured. Results were plotted against infant’s weight.

Results A weight-based chart and recommendations for the optimal intratracheal catheter position in infants with a body weight between 350 and 4000 g were created.

Conclusions Generated data offer standardisation and may thus help to find a balance between risk of surfactant reflux and unilateral surfactant administration.

  • neonatology
  • therapeutics

Data availability statement

All data relevant to this data analysis are included in the article or uploaded as supplemental information.

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