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Variation in prognosis given by fetomaternal units in fetuses with neurological abnormalities
  1. Anthony Hart1,
  2. Nicolas Embleton2,
  3. Cara Mooney3,
  4. Mike Bradburn3,
  5. Paul David Griffiths4
  1. 1Paediatric Neurology, Sheffield Children’s NHS Foundation Trust, Sheffield, UK
  2. 2Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
  3. 3School of Health and Related Research, The University of Sheffield, Sheffield, UK
  4. 4Academic Radiology, University of Sheffield, Sheffield, UK
  1. Correspondence to Dr Anthony Hart, Paediatric Neurology, Sheffield Children’s NHS Foundation Trust, Sheffield S10 5DD, UK; a.r.hart{at}

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The ‘MRI to enhance the diagnosis of fetal developmental brain abnormalities in utero’ (MERIDIAN) study showed improved diagnostic accuracy and confidence for detecting fetal neurological abnormalities compared with ultrasound. The additional information provided by in utero MRI altered prognosis in 44% of women, although clinicians reported it changed prognosis in only 24%.1 2 The reasons for this discrepancy are not clear, and the MERIDIAN study did not report whether the neurodevelopmental prognoses given to women varied between clinicians or were accurate.

We contacted one clinician at each of the MERIDIAN fetomaternal units and asked what percentage chance of normal neurodevelopmental outcome they would give pregnant women …

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