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Use of neurally adjusted ventilator assist in postsurgical hemidiaphragmatic paralysis
  1. Yohan Soreze,
  2. Emmanuelle Motte,
  3. Valentina Dell’Orto,
  4. Nadya Yousef,
  5. Daniele De Luca
  1. Division of Paediatrics and Neonatal Critical Care, “A. Béclère” Medical Centre, South Paris University Hospitals, APHP, Paris, France
  1. Correspondence to Dr Daniele De Luca, Service de Reanimation Neonatale, GHU Paris Sud, Hopital “A. Béclère”, 157 rue de la Porte de Trivaux, 92140 Clamart (Paris), France; dm.deluca{at}

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There are presently only scant data published about neonatal diaphragmatic paralysis and the options for its clinical management. We observed a case of unilateral diaphragmatic paralysis secondary to thoracic surgery in a preterm neonate, and we successfully managed it using neurally adjusted ventilator assist (NAVA) whose data have been electronically recorded in real time. Parents gave written consent for publication.

A preterm female baby, born at 25 weeks’ gestation, was diagnosed with haemodynamically patent ductus arteriosus, which needed surgical closure since two cures of ibuprofen failed to close it. After the surgery, she could not be weaned from mechanical ventilation for 26 days; chest X-rays revealed elevation of the left hemidiaphragm and targeted ultrasound confirmed the hemidiaphragmatic paralysis. The patient was shifted to invasive NAVA with Servo-i (Maquet, Solna, Sweden) and then finally extubated on biphasic positive airway pressure ventilation (BiPAP) through a nasal mask, as this is our routine clinical protocol. The NAVA level used was set at 4 cmH2O/μV and gradually decreased to 1 by steps of 0.5 cmH2 …

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  • Contributors YS, EM and VDO collected the data, managed the case and wrote the first paper draft. NY and DDL conceived the study, supervised it and did the statistical analysis. All authors reviewed the paper for important intellectual contents and approved its final version.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.