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The 2012 National Institute for Health and Care Excellence (NICE) guideline for prevention and treatment of neonatal early onset sepsis (EOS)1 has been subject to much debate since its publication. We have read with interest the experiences from other maternity units2–5 that have adopted this guideline. In contrast to these negative experiences, in Glasgow we have observed a positive impact following implementation in two large perinatal centres.
The recommended changes aim to prioritise antibiotic treatment for infants most likely to develop EOS, while minimising antibiotic exposure and reducing hospital stay for those at less risk. NICE …
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