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Stoltz Sjöström et al1 have demonstrated that higher intakes of energy, fat and carbohydrates, but not protein, were significantly associated with a lower risk of severe retinopathy of prematurity (ROP). Based on their current results and previous published studies, they propose a mechanism for the first phase of ROP pathogenesis. In this model, they suggest that a low-energy intake during the first 4 weeks of life can lead to arrested vascularisation. We commend the authors for this observation as well as for their comprehensive review of ROP pathogenesis.
However, although …
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