Objective To audit a specialist antenatal clinic at St Mary’s hospital in managing obstetric patients with renal disease and evaluate pregnancy outcomes in those patients against set standards.
Methods Data from patients with pre-existing renal disease managed in the clinic from January 2007 to December 2011 was included in the study. CKD staging was based on pre-conception eGFR or serum creatinine levels.
Results 117 singleton cases from 108 patients were analysed. Antenatal management standards had showed a satisfactory level with 1 in 4 women receiving a preconception advice, half of women starting prophylactic aspirin before 16 weeks with higher rate (65%) of prescribing in 2011. Pregnancy outcomes showed increased risk of pre-eclampsia development and preterm delivery along with Caesarean section compared to general population even with mild renal impairment. The highest rates of pregnancy complications were observed in severe renal impairment group with ¼ risk of not completing pregnancy.
Aspirin prophylaxis showed some reducing effect on the development of PET in different groups compared to no aspirin prophylaxis.
Conclusion There is a promising outlook in improvement of pregnancy outcomes in mild to moderate impaired kidney function pregnancies.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.