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PM.94 The Management of a Twin Pregnancy in a Patient with MAGIC Syndrome
  1. A Fabre-Gray,
  2. D Mahendran
  1. Gloucestershire Royal NHS Foundation Trust, Gloucester, UK


In 1985 Firestein et al, first described patients with co-existent relapsing polychondritis and Behçet’s Disease. They proposed the acronym MAGIC syndrome (Mouth And Genital ulcers with Inflamed Cartilage).

This is a rare condition with no more than twenty cases described in the literature to date.

This case is the first to report the management of a pregnancy in a patient with MAGIC syndrome.

The autoimmune pathogenesis can potentially damage cartilage anywhere in the body, including cardiac valves and tracheal cartilage. Therefore a multidisciplinary approach to the management of this pregnancy was paramount.

We describe her antenatal, intrapartum and post-partum management specific to this condition and demonstrate how this led to a safe delivery of her twins.

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