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Images in neonatal medicine
Human herpesvirus-6 associated neonatal urticaria multiforme
  1. Alessandro Borghesi1,
  2. Paola Cipelletti1,
  3. Roberta Maragliano1,
  4. Paolo Manzoni2,
  5. Mauro Stronati1
  1. 1Neonatologia, Patologia Neonatale e Terapia Intensiva, Fondazione IRCCS Policlinico “San Matteo”, Pavia, Italy
  2. 2Neonatology and Neonatal Intensive Care Unit, S. Anna Hospital, Azienda Ospedaliera Regina Margherita-S. Anna, Torino, Italy
  1. Correspondence to Alessandro Borghesi, Fondazione IRCCS Policlinico San Matteo, Piazzale Golgi n. 19, 27100, Pavia, Italy; alessandroborghesi{at}

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An 18-day-old neonate was referred to our hospital because of an urticarial rash that had appeared a few hours before. On examination, skin lesions were present on the face, trunk, arms and legs. These appeared as sharply demarcated, erythematous and infiltrated, irregularly shaped, and partially desquamating papules and plaques. The infant appeared otherwise healthy, neither with lymphadenopathy nor hepatosplenomegaly. Pregnancy history was unremarkable, and serologic tests …

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