Article Text

Download PDFPDF
Congenital diaphragmatic hernia with(out) ECMO: impaired development at 8 years


Objective To evaluate developmental and social-emotional outcomes at 8 years of age for children with congenital diaphragmatic hernia (CDH), treated with or without neonatal extracorporeal membrane oxygenation (ECMO) between January 1999 and December 2003.

Design Cohort study with structural prospective follow-up.

Setting Level III University Hospital.

Patients 35 children (ECMO: n=16; non-ECMO: n=19) were assessed at 8 years of age.

Interventions None.

Main outcome measures Intelligence and motor function. Concentration, behaviour, school performance, competence and health status were also analysed.

Results Mean (SD) intelligence for the ECMO group was 91.7 (19.5) versus 111.6 (20.9) for the non-ECMO group (p=0.015). Motor problems were apparent in 16% of all participants and differed significantly from the norm (p=0.015) without differences between treatment groups. For all participants, problems with concentration (68%, p<0.001) and with behavioural attention (33%, p=0.021) occurred more frequently than in reference groups, with no difference between treatment groups. School performance and competence were not affected.

Conclusions Children with CDH—whether or not treated with neonatal ECMO—are at risk for long-term morbidity especially in the areas of motor function and concentration. Despite their impairment, children with CDH have a well-developed feeling of self-competence.

  • Congenital Abnorm
  • Ecmo
  • Neurodevelopment
  • Outcomes research
  • Intensive Care

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.