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Contributors PL and SM are responsible for reported research; PL and SM have participated in the concept and design, analysis and interpretation of data, drafting or revising of the manuscript, and have approved the manuscript as submitted.
Funding Rouen University Hospital Charles Nicolle, INSERM, Rouen University and FEDER.
Competing interests None.
Patient consent Obtained.
Ethics approval Advice number CCPPRB: DGS 2006/0378 (7.08.2006).
Provenance and peer review Not commissioned; internally peer reviewed.