Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Whole body cooling improves outcomes after neonatal encephalopathy (NE) in high-income countries1; however, effective low technology cooling devices suitable for use in low and middle-income countries (LMIC) is lacking.2 Although cooling using ice is effective in tertiary neonatal units, dangerous temperature fluctuations may occur if continuous temperature monitoring and nursing support is not available.2 Phase changing materials (PCM) are made of salt hydride, fatty acid, and esters or paraffin, and melt at a set point; in the process they can store or release large amounts of energy (figure 1). We examined the feasibility of administering whole body cooling using PCM.
Contributors ST conceived the idea, designed the study along with SS, and GB, analysed the data, drafted the manuscript, and had the final responsibility for all aspects of the study. MA, KS and CS recruited the cases, collected data and performed neurological assessments. AW advised on randomisation and supervised the data analysis. All authors contributed towards manuscript development and approved the final draft for publication. The study is compliant with the TRUST (Transparent Research Audit System) guidelines for ensuring research quality and integrity.
Competing interests None.
Patient consent Obtained.
Ethics approval Ethics Committee, University College London.
Provenance and peer review Not commissioned; externally peer reviewed.
Clinical trials.gov No NCT01138176