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Distinguishing duct dependent congenital heart disease (DDCHD) from other causes of hypoxaemia, notably persistent pulmonary hypertension (PPHN), represents a diagnostic and therapeutic dilemma for neonatal transport teams, specifically in relation to use of prostaglandin E1 (PGE1). In non-DDCHD, PGE1 is considered unnecessary and likely to produce unwanted side-effects including apnoea and hypotension.1
We report our observations of the effects of PGE1 infusion in a group of babies with evidence of PPHN but without DDCHD.
We reviewed the data on all infants ≤10 days and ≥34 weeks gestation with suspected DDCHD and/or PPHN transferred by the Newborn Emergency Transport Service (NETS), Victoria, from non-tertiary neonatal units to the regional paediatric cardiac …
Contributors All authors were responsible for planning and reporting. NG and NP conducted the data collection and analysis.
Competing interests None.
Ethics approval Royal Children's Hospital, Melbourne, Australia.
Provenance and peer review Not commissioned; externally peer reviewed.
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