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Newborn screening of congenital cytomegalovirus infection using saliva can be influenced by breast feeding
  1. Shin Koyano1,
  2. Naoki Inoue2,
  3. Tsunehisa Nagamori1,
  4. Hiroyuki Moriuchi3,
  5. Hiroshi Azuma1
  1. 1Department of Paediatrics, Asahikawa Medical University, Asahikawa, Japan
  2. 2Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan
  3. 3Department of Paediatrics, Nagasaki University, Nagasaki, Japan
  1. Correspondence to Dr Shin Koyano, Department of Paediatrics, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa 078-8510, Japan; koyano5p{at}

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Congenital cytomegalovirus (cCMV) infection occurs in 0.2–2% of all births in developed countries and causes developmental abnormalities.1 In addition to patients symptomatic at birth, asymptomatic newborns can develop late-onset sequelae, including sensorineural hearing loss and developmental delay. As the early identification of congenitally infected newborns may allow early intervention and antiviral treatment options, it is important to establish newborn cCMV screening programmes.

Since newborn screening assays using dried blood spots for cCMV infection were …

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  • Funding This work was supported by Grants for the Research on Child Development and Diseases (H23-Jisedai-Ippan-001) from the Ministry of Health, Labor and Welfare, Japan.

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval Asahikawa Medical University.

  • Provenance and peer review Not commissioned; externally peer reviewed.