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Trends in the incidence of retinopathy of prematurity in Lothian, south-east Scotland, from 1990 to 2009
  1. Shi Zhuan Tan1,
  2. Catharine Dhaliwal2,
  3. Julie-Clare Becher3,
  4. Brian Fleck4
  1. 1Department of Ophthalmology, Manchester Royal Eye Hospital, Manchester, UK
  2. 2Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK
  3. 3Neonatal Unit, Simpson Centre for Reproductive Health, Royal Infirmary of Edinburgh, Edinburgh, UK
  4. 4Department of Ophthalmology, Princess Alexandra Eye Pavilion, Edinburgh, UK
  1. Correspondence to Shi Zhuan Tan, Department of Ophthalmology, Manchester Royal Eye Hospital, Oxford Road, Manchester M13 9WL, UK; shizhuan{at}

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Retinopathy of prematurity (ROP) is a disorder of retinal vascular development in premature infants and is a major cause of childhood blindness worldwide. Dhaliwal et al conducted a prospective, population-based study looking at the incidence of ROP in the Lothian region of south-east Scotland from 1990 to 2004 and found the following1:

  • (1) Significant increase in survival of infants with birth weight <1500 g and/or gestational age <32 weeks

  • (2) Significant reduction in the number of infants treated for ROP

  • (3) Reduction in the incidence of any degree of ROP and severe (stage 3 or greater) ROP although both did not reach statistical significance.

Treatment criteria for ROP have changed in Lothian …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.