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Childhood outcome of antenatally diagnosed cleft lip and palate
  1. E G Zhang,
  2. M Heidary-Seradji,
  3. G Paramasivam,
  4. E Nobili,
  5. S Kumar
  1. Imperial College, London, UK


The objective of this study was to analyse the childhood outcome of antenatally diagnosed cleft lip palate. This was an observational study from 2002 to 2008. During the study period there were 82 cases identified antenatally with a resultant 57 live births. Follow-up data on 44 cases (44/57, 77%) were obtained with a follow-up age ranging from 24 to 50 months. The majority of cases (22 cases, 50%) had a single operation, followed by 20 cases (45.5%) who had two operations and only two cases (4.5%) had three operations. Of the 44 cases, 26 (59.1%) required speech therapy, 14 (31.8%) needed further dental treatment/surgery and 4 (9.1%) needed additional otorhinological treatment. Only 4 cases (9.1%) required ophthalmology follow-up. Only two (4.5%) children had significant feeding problems. All parents reported are happy with the cosmetic outcome following surgery.

Conclusion Although a slight majority of cases in this series required a single operative procedure a significant number also required two surgical procedures. The most common post-surgical complication was speech difficulties.

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