Article Text

Download PDFPDF
Changes in neonatal morbidity after rcog guideline 44 for preterm prelabour rupture of membranes
  1. N Oswald,
  2. Z Anwar,
  3. F Mackenzie,
  4. C Lilley
  1. Princess Royal Maternity Hospital, Glasgow, UK


Introduction The RCOG published Guideline 44 in November 2006 for the management of preterm prelabour rupture of membranes, recommending delivery at 34 weeks. Concern was raised that this may have had a detrimental effect on neonatal morbidity.

Objective Assess the impact on neonatal admissions following introduction of Guideline 44.

Methods Retrospective review of singleton preterm deliveries, 34–36+6 weeks with PPROM: pre-guideline (1 April 2005–31 March 2006) and post-guideline (1 April 2008–31 March 2009). Case note review of NNU admissions.

Results Pre-guideline: 5155 deliveries; 50 pre-term following PPROM; 17 NNU admissions. Post-guideline: 5694 deliveries; 52 pre-term following PPROM; 14 NNU admissions.

Conclusion Implementing the recommendation to deliver women with PPROM at 34 weeks does not appear to cause an increase in NNU admissions, however those admitted have a greater morbidity. Further information will be attained by reviewing all women with PPROM over the study periods.

Abstract PA.09 Table 1

Pregnancy results and neonatal outcome

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.