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Preterm neonates experience a large number of painful procedures during their stay in the neonatal intensive care units (NICUs) and these procedures are often not accompanied by satisfactory analgesia.1 2 Peripherally inserted central catheter (PICC) insertion is a painful intervention employed recurrently to provide a secure venous access.3,–,7
The aim of this study was to determine whether 25% oral glucose or EMLA cream was a better strategy for controlling pain in preterm neonates undergoing PICC insertion.
A randomised, triple-masked controlled trial was conducted at two tertiary NICUs in the city of Belo Horizonte, Brazil. Participants included 30 preterm neonates (≥28 and <37 weeks of gestational age) during the first week of life with a clinical indication …
Competing interests None.
Patient consent Obtained.
Ethics approval This study was conducted with the approval of the Research Ethics Committee of Neonatal Division of the Hospital of the Federal University of Minas Gerais and Neonatal Division of Julia Kubitschek Hospital in the city of Belo Horizonte, Brazil.
Provenance and peer review Not commissioned; externally peer reviewed.