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Routine probiotics in preterm infants?
  1. Florian Guthmann,
  2. Christoph Bührer
  1. Department of Neonatology, Charité Universitätsmedizin Berlin, Berlin, Germany
  1. Correspondence to Christoph Bührer, Department of Neonatology, Charité Universitätsmedizin Berlin, Berlin D-13344, Germany; christoph.buehrer{at}

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A commissioned commentary by Millar et al1 and a recent statement from the American Academy of Pediatrics2 complain about the lack of defined probiotic products that are licensed by regulatory authorities. A commercially available combination of Lactobacillus acidophilus and Bifidusbacterium infantis (Infloran), given to a total of 1725 preterm infants within the framework of two open-label and two randomised controlled trials without side effects,3 has been shown to reduce necrotising enterocolitis (NEC) and …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.