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Incidence of severe hyperbilirubinaemia in Switzerland: a nationwide population-based prospective study
  1. S Zoubir1,
  2. R Arlettaz Mieth2,
  3. S Berrut3,
  4. M Roth-Kleiner1,
  5. the Swiss Paediatric Surveillance Unit (SPSU)
  1. 1Department of Pediatrics, Clinic of Neonatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
  2. 2Clinic of Neonatology, University Hospital of Zurich, Zurich, Switzerland
  3. 3Swiss Federal Office of Statistics, Neuchâtel, Switzerland
  1. Correspondence to M Roth-Kleiner, Department of Pediatrics, Clinic of Neonatology, Centre Hospitalier Universitaire Vaudois, Avenue Pierre Decker, CH-1011 Lausanne, Switzerland; matthias.roth{at}

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Epidemiological data about severe hyperbilirubinaemia in neonates are scarce. We present results of a nationwide prospective study conducted in collaboration with the Swiss Federal Office for Public Health and the Swiss Paediatric Surveillance Unit (SPSU). Data for all newborn patients ≥35 0/7 weeks of gestational age (GA) born between 1 January 2007 and 31 December 2008 with at least one value of total serum bilirubin (TSB) exceeding the upper limit of exchange transfusion (ET) were included. ET limits are defined as 430 μmol/l for healthy term infants; 370 μmol/l for sick term infants or term infants with haemolysis and 320 μmol/l for preterm infants.1 A check-off form asking for neonates hospitalised with severe hyperbilirubinaemia and a detailed questionnaire were sent to all neonatal and …

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  • Swiss Paediatric Surveillance Unit representatives C Aebi, W Bär, M Bianchetti, A Blumberg, H U Bucher, L Buetti, O Carrel, P O Cattin, A Corboz, P Diebold, P Dolivo, F Farron, M Gehri, E Giannoni, C A Haenggeli, P Hüppi, P Imahorn, C Kind, B Knöpfli, B Laubscher, U Lips, A Malzacher, J Mc Dougall, P Meyer, M Mönkhoff, V Pezzoli, K Posfay Barbe, L Reinhard, F Renevey, H Roten, C Rudin, V Schlumbom, S Sizonenko, C Stüssi, R Tabin, P Terrier, J Wildhaber, M Wopmann, G Zeilinger, A Zemmouri, U Zimmermann.

  • Competing interests None.

  • Ethics approval This study was conducted according to the ethical guidelines of the SPSU and approved by the ethics committee of the University Hospital of Zurich.

  • Provenance and peer review Not commissioned; externally peer reviewed.