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Network meta-analysis of indomethacin versus ibuprofen versus placebo for PDA in preterm infants
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    Ibuprofen and Chronic lung disease association: Is this clinically significant?

    Dear Sir,

    We read the article by Jones et al with great interest describing Ibuprofen may increase the risk of chronic lung disease (CLD) compared to Indomethacin. We are unsure whether the data presented is fully supportive of the conclusion that Ibuprofen poses a greater risk of CLD compared to Indomethacin and whether this is clinically significant.

    In Figure 4 the pooled risk ratio (RR) was 1.28 (95...

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    Conflict of Interest:
    None declared.