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Is remifentanil an option for premedication for neonatal endotracheal intubation?
  1. Yerkes Pereira e Silva1,2,
  2. Juliana de Oliveira Marcatto1,
  3. Rosilu Ferreira Barbosa1,
  4. Ana Cristina Simões e Silva1
  1. 1Department of Pediatrics, Federal University of Minas Gerais, Belo Horizonte, Brazil
  2. 2Department of Anesthesia, Lifecenter Hospital, Belo Horizonte, Brazil
  1. Correspondence to Yerkes Pereira e Silva, Rua Montevidéu, 402 Apto. 402, Belo Horizonte, Minas Gerais 30315560, Brazil; yerkesps{at}

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It was with great interest that we read the article by Choong et al, ‘Remifentanil for endotracheal intubation in neonates: a randomised controlled trial’.1 First of all, we would like to congratulate the authors on their randomised controlled trial (RCT). However, there are some issues that should be raised.

The premedication protocol for endotracheal intubation in this study includes many classes of drugs besides opioids that might interfere with physiological responses. For instance, the administration of …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.