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Thresholds for antibiotic resistance at which we change empirical treatment choices
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  • Published on: 22 March 2016
    Response to 'Thresholds for antibiotic resistance at which we change empirical treatment choices' (Postscript ADC November 2010, Volume 95, Issue 6)
    • Berit Muller-Pebody, Epidemiologist
    • Other Contributors:
      • Alan P. Johnson, Paul T. Heath, Ruth E. Gilbert, Katherine L. Henderson, Mike Sharland

    Dr. Millar raises the point that an alternative broader-spectrum (and more expensive) antibiotic combination could be considered for empirical therapy of neonates with suspected early-onset sepsis in preference to penicillin and gentamicin which (based on our data) he estimated to be ineffective for 6% of cases.

    We support Dr Millar's view on the importance of appropriate empirical antibiotic treatment for septi...

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    Conflict of Interest:
    None declared.