Article Text

This article has a correction. Please see:

Download PDFPDF
Systemic inflammatory response syndrome (SIRS) definition and correlation with early-onset bacterial infection of the newborn
  1. N Hofer,
  2. W Miiller,
  3. B Resch
  1. Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria
  1. Correspondence to: Nora Hofer, Division of Neonatology, Pediatric Department, Medical University of Graz, Auenbruggerplatz 30, A-8036 Graz, Austria; norahofer{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

In 2002 the International Pediatric Sepsis Consensus Conference created definitions for the systemic inflammatory response syndrome adaptable for children from term neonates to adolescents as entry criteria for clinical trials for making studies easier to compare.1 So far their applicability in term and preterm newborns with correlation to early-onset bacterial infection (EOBI) has not been evaluated.

In a retrospective analysis of all newborns aged below 3 days, hospitalised at a tertiary care neonatal intensive care unit, 214 of 662 neonates (32%) were positive regarding systemic inflammatory response syndrome SIRS) criteria (two out of four criteria, points (a) or …

View Full Text


  • Competing interests: None.

  • Provenance and peer review: Not commissioned; externally peer reviewed.

Linked Articles

  • Postscript
    BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health