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Cord blood, perinatal BNP values in term and preterm newborns
  1. S Mannarino1,
  2. F Garofoli2,
  3. R M Cerbo2,
  4. G Perotti2,
  5. E Mongini2,
  6. C Codazzi1,
  7. L Ciardelli3,
  8. C Tinelli4,
  9. A DeSilvestri4,
  10. M Stronah2
  1. 1
    Pediatric Cardiology, Department of Paediatrics, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  2. 2
    Neonatology NICV and Neonatal Immunology Lab, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  3. 3
    Microbiology Laboratory, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  4. 4
    Biometric Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  1. Correspondence to Dr Francesca Garofoli, Fondazione IRCCS Policlinico S. Matteo, Neonatal Immuunology Lab, NICU, Piazzale Golgi, 1, Pavia 27100, Italy; lab.immunoneo{at}

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The number of studies about B-type natriuretic peptide (BNP) and neonates is growing; nevertheless, the use of BNP needs to be further investigated in preterm newborns.1 2 We observed the pattern of plasma BNP concentrations from late fetal life, from umbilical cord blood (UBC) samples, through day 1 of life (preterm only), day 3, and until the first month of life in 32 preterm newborns and 32 full-term healthy newborns. The results are summarised below.

Median preterm newborns’ BNP concentrations: UBC, 31 pg/ml (interquartile range (IQR): 7.2–98.6); birth day, 84.4 pg/ml (IQR: 30.6–471.5); day 3, 35.7 pg/ml (IQR: 14.2–119.7); day 30, 12.7 pg/ml (IQR: 5–16.2). Median full-term newborns’ BNP concentrations: UCB, 10.6 …

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  • Competing interests None.

  • Provenance and Peer review Not commissioned; externally peer reviewed.

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