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Neonatal outcomes of macrosomic births in diabetic and non-diabetic women
  1. S Das,
  2. M Irigoyen,
  3. M B Patterson,
  4. A Salvador,
  5. D L Schutzman
  1. Department of Pediatrics, Division of Neonatology, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA
  1. Correspondence to Dr David L Schutzman, Albert Einstein Medical Center, 5501 Old York Road, Philadelphia, PA 19141, USA; schutzmand{at}


Objective: To compare the neonatal outcomes and birth injuries of macrosomic infants born to diabetic mothers (IDM) and non-diabetic mothers (non-IDM).

Study design: This is a retrospective survey of all live born, singleton neonates with a birth weight of ⩾4000 g, delivered at the Albert Einstein Medical Center, Philadelphia during a 3-year period (2003 through 2005). 305 infants of the 7158 delivered during this period met entry criteria. Data were analysed using χ2 and Fisher’s exact test. Logistic regression analysis was also performed.

Result: Compared to IDMs, non-IDMs were born later (40 vs 38 weeks) and were more likely to be delivered vaginally (70% vs 34%). Half of the non-IDMs (49.6%) had at least one morbidity compared with 73.2% of the IDMs. Non-IDMs had a higher incidence of birth injury than IDMs (8% vs 2.4%). Logistic regression showed an increased risk of poor outcome with weight ⩾4500 g and vaginal delivery.

Conclusion: All macrosomic infants represent a high-risk group, regardless of maternal diabetes status.

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  • Funding None.

  • Competing interests None.

  • Patient consent This study received exemption from the requirement for informed consent from the Institutional Review Board of the Albert Einstein Medical Center.

  • Provenance and Peer review Not commissioned; externally peer reviewed.