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Red cell transport and transfusion in preterm infants
  1. J Gueguen3,
  2. A Beuchée1,2,3,
  3. T Gaillot3,
  4. P Bétrémieux3,
  5. P Pladys1,2,3
  1. 1
    INSERM, U642, Rennes, France
  2. 2
    Université de Rennes, LTSI, Rennes, France
  3. 3
    CHU Rennes, Pôle médico-chirurgical de Pédiatrie et de génétique clinique, Néonatologie, CHU Rennes, Rennes, France
  1. Dr P Pladys, Pôle médico-chirurgical de Pédiatrie et de génétique clinique, Néonatologie, CHU Rennes, Laboratoire INSERM U642 de traitement du signal et de l’image, université de Rennes 1, Pav. Le Chartier – 2 R H Le Guilloux – 35033 Rennes Cedex 9; patrick.pladys{at}chu-rennes.fr

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In preterm infants, cardiac output increases when haematocrit decreases.1 Red cell transport (RCT), which is the product of the cardiac output and haematocrit and represents the oxygen-carrying capacity, increases after neonatal red cell transfusion for anaemia.2 3 We wanted to test if a low RCT could predict a beneficial clinical response (decrease in bradycardia frequency) to red cell transfusion. Eleven preterm infants (table 1) were studied before and 24 h after a 20 ml/kg red cell transfusion that was given based on pre-established criteria.4 Infants …

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Footnotes

  • Funding: This study was supported by the Rennes teaching hospital research committee (COREC).

  • Competing interests: None.