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Renovascular hypertension commencing during fetal life
  1. Shivaram Hegde1,
  2. Christopher Wright2,
  3. Mohan Shenoy1,
  4. Nadeem E Moghal1,
  5. Malcolm G Coulthard1
  1. 1Departments of Paediatric Nephrology, Royal Victoria Infirmary, Newcastle, UK
  2. 2Departments of Pathology, Royal Victoria Infirmary, Newcastle, UK
  1. Correspondence to:
    Malcolm G Coulthard
    Departments of Paediatric Nephrology, Royal Victoria Infirmary, Newcastle, NE1 4LP; malcolm.coulthard{at}


We report three infants with severe, early hypertension due to unilateral renovascular disease, whose cardiovascular changes, or polycythaemia, or both, indicated they had been affected as fetuses. All underwent unilateral nephrectomy, and had a similar histology, with patchy areas having relatively normal glomeruli but immature proximal tubules. This pattern may be a marker for renovascular disease in fetal life.

  • DMSA, dimercaptosuccinic acid
  • EMA, epithelial membrane antigen
  • FENa, fractional excretion of sodium

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  • Competing interests: None declared.