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Conservative treatment for patent ductus arteriosus in the preterm
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  • Published on:
    Conservative treatment for patent ductus arteriosus
    • Rajeshwar Reddy Angiti, Senior Registrar in Neonatology
    • Other Contributors:
      • Martin Kluckow MBBS, FRACP, PhD Senior staff specialist in Neonatology

    Dear Editor,

    We read with interest the article by Vanhaesebrouck S et al[1]. We support the author's aims to properly study the role of conservative management of PDA, but advise caution in accepting their conclusions from results of such a small study. In their introduction the authors refer to the known consequences of a left to right shunt when a PDA is clinically significant, including IVH, NEC and chronic...

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    Conflict of Interest:
    None declared.
  • Published on:
    Risks of conservative management of patent ductus arteriosus in preterm infants
    • Eleanor J Molloy, Consultant Neonatologist
    • Other Contributors:
      • Roberta McCarthy and Afif El-Khuffash

    Dear Editor,

    We read with interest the recent article by Vanhaesebrouck S et al describing the conservative management of preterm infants with a patent ductus arteriosus (PDA). We would be interested in the duration of the fluid restriction and the impact on infant growth and kcal/kg/day. From our calculations, expressed human milk with the addition of human milk fortifier (e.g. Nutriprem: approx 85kcals plus 2.3g...

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    Conflict of Interest:
    None declared.
  • Published on:
    Adjustment of ventilation for treatment of patent ductus arteriosus

    Dear Editor,

    An interesting aspect is that the combination of adjustment of ventilation and fluid restriction achieved an overall ductal closure rate of 100%. There is no evidence for any effect of differing ventilation modalities upon the incidence of PDA.

    Both inspiratory time and positive end expiratory pressure (PEEP) can affect the mean airway pressure during mechanical ventilation. But mean airwa...

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    Conflict of Interest:
    None declared.
  • Published on:
    Complication rates

    Dear Editor,

    I found this article interesting but found the data presented in Table 2 regarding complication rates to be confusing. An n value of 30 is given for the conservative treatment group. However only 10 babies were "treated" for their PDA, 20 babies did not have a PDA. Therefore is it correct to compare percentage rates with studies of babies who did have a PDA?

    2% of this group had a grade 3 IV...

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    Conflict of Interest:
    None declared.