Statistics from Altmetric.com
Haemolytic disease of the newborn (HDN) is caused by maternal immunoglobulin (Ig) G acting against antigens expressed on mature fetal red cells. Anti-M antibodies active at 37°C are a rare cause of HDN.1 We report data, arising from the investigation of a neonate with severe transient pure red-cell aplasia, indicating that anti-M can cause hypoplastic HDN by inhibition of erythroid precursor growth, as frequently occurs with anti-Kell antibodies.2
A female neonate presented at 4 weeks of age with severe hypoplastic anaemia (haemoglobin 3.7 g/dl, reticulocytes …
Competing interests: None declared.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.