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An international replication, and the need for long term follow up studies
  1. Z Vekerdy1,
  2. L Lakatos2,
  3. G Balla3,
  4. G Oroszlan4
  1. 1National Institute for Medical Rehabilitation, Department of Children’s Rehabilitation, Budapest, Hungary
  2. 2Kenezy County Hospital, Debrecen, Bartók, Hungary
  3. 3NICU, University Medical School, Debrecen, Hungary
  4. 4Markusovszky County Hospital, Szombathely, Hungary
  1. Correspondence to:
    Professor Lakatos
    Kenezy County Hospital, Debrecen, Bartók B.u. 2-26., H-4043; lakatosl{at}

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In 1999, a provocative letter was published in your journal1 concerning the use of d-penicillamine (DPA) in the neonatal period. The following statement was written: “Why, then, we wonder, has the demonstration of an effective mode of prevention of retinopathy of prematurity (ROP) in two randomised trials conducted more than 10 years ago in Hungary,2 failed to encourage others to undertake the independent replications needed to verify or refute such a promising approach?”

Now, we …

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  • Competing interests: None declared.