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A randomised, double blind, placebo controlled trial of the effect of theophylline in prevention of vasomotor nephropathy in very preterm neonates with respiratory distress syndrome
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    Is theophylline safe to use for treatment of vasomotor nephropathy in preterm infants?

    Dear Editor,

    Catterelli et al(1) suggest that early theophylline administration improves renal function during the first two days of life in very preterm infants with RDS. We are concerned that this very short term outcome could be over interpreted if the long-term outcome is not taken into consideration.

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    Conflict of Interest:
    None declared.