You are here

Article Text

Article menu
Download PDFPDF
Short report
Sildenafil in neonatal pulmonary hypertension due to impaired alveolarisation and plexiform pulmonary arteriopathy

Abstract

We report a case of severe pulmonary hypertension in a neonate associated with impaired alveolarisation and plexiform pulmonary arteriopathy. Treatment with oral sildenafil in addition to inhaled nitric oxide (NO) resulted in recovery from the pulmonary hypertensive crisis. Long term sildenafil therapy was associated with complete resolution of the pulmonary hypertension.

  • BSA, body surface area
  • cGMP, cyclic-guanosine 5 monophosphate
  • ECG, electrocardiogram
  • ECMO, extra-corporeal membrane oxygenation
  • NO, nitric oxide
  • PPHN, persistent pulmonary hypertension of the newborn
  • RV, right ventricular
  • RVH, right ventricular hypertrophy
  • TR, tricuspid valve regurgitation
  • impaired alveolarisation
  • nitric oxide
  • persistent pulmonary hypertension of neonate
  • sildenafil

https://doi.org/10.1136/adc.2004.062885

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.