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Inadvertent overdosing of neonates as a result of the dead space of the syringe hub and needle
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  • Published on:
    Re: Inadvertent overdosing of neonates
    • Anjali S. Bangalore, Lecturer in Paediatrics
    • Other Contributors:
      • Deemed University Medical College, Pune

    Dear Editor,

    I agree with you that there can be overdosage while administrating IV medications in neonates. These are few of the precautions we take in our neonatal unit to avoid medication errors.

    1. The required quantity of diluent is first drawn in the syringe and then the required amount of the drug is drawn in the syringe and quantity measured in the middle part of the syringe.

    2. Required qua...

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    Conflict of Interest:
    None declared.
  • Published on:
    Avoiding another source of dilutional errors

    Dear Editor,

    Both Drs. Bhambhani and Richmond miss an important point in discussing methods to avoid syringe dead space errors in diluting medications for neonatal dosing. The assumption that volumes as small as 0.02 cc can be accurately measured with a 1 cc syringe is erroneous. A number of years ago I was investigating the etiology of wildly erratic gentamicin levels and learned that the syringe manufacturer on...

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    Conflict of Interest:
    None declared.
  • Published on:
    Avoiding the syringe dead space

    Dear Editor,

    There is a simpler solution to the problem of the syringe dead space when diluting drugs which was raised by Dr Bhambani et al. and that is to draw some of the diluent into the syringe first. Perhaps I may be allowed to quote from the section on neonatal drug administration on page 5 of the Neonatal Formulary (4th edition, 2003 -

    "Many drugs have to be diluted be...

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    Conflict of Interest:
    None declared.