You are here

Article Text

Article menu
Download PDFPDF
Short report
Nasal potential difference increases with gestation in moderately preterm neonates on the first postnatal day
  1. E A Gaillard1,
  2. N J Shaw1,
  3. H L Wallace2,
  4. N V Subhedar1,
  5. K W Southern2
  1. 1Liverpool Women’s Hospital, Neonatal Unit, Crown Street, Liverpool L8 7SS, UK
  2. 2Institute of Child Health, University of Liverpool, Royal Liverpool Children’s Hospital, Alder Hey, Liverpool L12 2AP, UK
  1. Correspondence to:
    Dr Gaillard
    Respiratory Unit, Royal Liverpool Children’s Hospital, Eaton Road, Liverpool L12 2AP; gaillardliv.ac.uk

Abstract

At birth the mammalian airway switches from liquid secretion to absorption, an important mechanism in lung liquid clearance. Airway ion transport was examined on the first postnatal day in 38 moderately preterm infants (29–36 weeks gestation). The absorptive airway ion transport capacity was well developed regardless of respiratory condition and there was little capacity for Cl− secretion.

  • ENaC, epithelial sodium channel
  • PD, potential difference
  • airway epithelium
  • chloride transport
  • epithelial sodium channel
  • respiratory distress
  • sodium transport

http://dx.doi.org/10.1136/adc.2004.054494

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • Funding: EAG was supported by the Liverpool Women’s Hospital “Newborn Appeal”. HLW was supported by the Medical Research Council, UK.

    • Competing interests: none declared