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Lower placental weight is associated with raised cord serum insulin concentrations at birth
  1. M Rodríguez-Morán1,
  2. F Guerrero-Romero1,
  3. M Levario-Carrillo2
  1. 1Medical Research Unit in Clinical Epidemiology of the Mexican Social Security Institute and Research Group on Diabetes and Chronic Illnesses, Durango, México; rodriguez_moran@hotmail.com
  2. 2Medical Research Unit in Clinical Epidemiology of the Mexican Social Security Institute, Chihuahua, México

https://doi.org/10.1136/adc.2004.064089

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    A growing body of evidence suggests that the malnourished fetus may develop peripheral insulin resistance1 and that low birth weight is a risk factor for metabolic and cardiovascular disease in adulthood.2,3 As intrauterine nutrition and fetal growth depends on the placenta, we hypothesise that low weight placenta may be linked to the increase in serum insulin concentration in small for gestational age (SGA) term newborn infants.

    We compared 20 SGA babies with 40 of appropriate size for gestational age (AGA) in a cross …

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    Footnotes

    • Competing interests: none declared