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In utero HIV infection in pregnancies complicated by tuberculosis in Durban, South Africa
  1. T Pillay1,
  2. M Adhikari1,
  3. H M Coovadia1,
  4. J Moodley2,3,
  5. M Khan3,
  6. J L Sullivan4
  1. 1Department of Paediatrics and Child Health, University of Natal Medical School, South Africa
  2. 2Department of Obstetrics and Gynaecology University of Natal Medical School
  3. 3Medical Research Council Pregnancy and Hypertension Unit, Durban, South Africa
  4. 4University of Massachusetts Medical School, Worcester, MA, USA
  1. Correspondence to:
    Dr Pillay
    Peter Medawar Building for Pathogen Research, Room 305.40.24, South Parks Road, University of Oxford, Oxford OX1 3SY, UK;

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At the core of the HIV-1 and tuberculosis (TB) epidemics, a defined effect of these combined pathogens on maternal and child health has been observed at King Edward VIII Hospital in Durban South Africa.1,2 Here we report on the adverse effect of maternal HIV-1 infection with TB disease on fetal acquisition of HIV-1.

In a prospective cohort study conducted at the hospital between April 1997 and July 1999, 42 HIV-1 infected pregnant women with active TB disease were investigated for …

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