Article Text

Download PDFPDF
DTP immunisation of steroid treated preterm infants
  1. P Clarke1,
  2. M J Robinson1,
  3. P J Powell2
  1. 1Neonatal Unit, Hope Hospital, Salford M6 8HD, UK;
  2. 2Department of Paediatrics, Royal Bolton Hospital, Bolton BL4 0JR, UK

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Preterm infants respond well to the three doses of diphtheria, tetanus, and whole cell pertussis (DTP) vaccine,1 but dexamethasone treatment may impair immunogenicity.2,3 We investigated whether four, rather than three, DTP doses may be preferable for primary immunisation of steroid treated preterm infants. Twelve infants born at < 30 weeks gestation who had received dexamethasone for chronic lung disease were given doses of DTP vaccine combined with Hib (ActHIB DTP; Pasteur-Mèrieux-MSD) at 2, 3, and 4 months of age. A fourth dose was administered six weeks after the third immunisation (table 1). With the use …

    View Full Text