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Case report
Exhaled nitric oxide in chronically ventilated preterm infants
  1. O Williams,
  2. R Y Bhat,
  3. P Cheeseman,
  4. G F Rafferty,
  5. S Hannam,
  6. A Greenough
  1. Children Nationwide Regional Neonatal Intensive Care Centre, 4th floor Ruskin Wing, King’s College Hospital, London SE5 9RS, UK
  1. Correspondence to:
    Professor A Greenough
    Children Nationwide Regional Neonatal Intensive Care Centre, 4th floor Ruskin Wing, King’s College Hospital, London SE5 9RS, UK; anne.greenoughkcl.ac.uk

Abstract

Exhaled nitric oxide (eNO) levels were measured in eight ventilated infants, mean gestational age 25.8 (SD 1.7) weeks and postnatal age 55 (SD 39) days, before and after three days of dexamethasone treatment. The eNO levels fell from a mean of 6.5 (SD 3.4) to 4.2 (SD 2.6) parts per billion (p = 0.031) and the mean supplementary oxygen levels from 62% to 45% (p = 0.0078).

  • exhaled nitric oxide
  • chronic lung disease
  • prematurity
  • eNO, exhaled nitric oxide
  • ppb, parts per billion
  • CLD, chronic lung disease
  • BAL, bronchoalveolar lavage
  • iNOS, inducible nitric oxide synthetase

https://doi.org/10.1136/fn.89.1.F88

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