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Subcutaneous fat necrosis of the newborn: hypercalcaemia with hepatic and atrial myocardial calcification
  1. J Dudink1,2,
  2. F J Walther1,
  3. R P Beekman1
  1. 1Department of Paediatrics, Divisions of Neonatology and Paediatric Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  2. 2Department of Paediatrics, Reinier de Graaf Gasthuis, Delft, The Netherlands
  1. Correspondence to:
    Dr Walther, Department of Paediatrics, Division of Neonatology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands;


Subcutaneous fat necrosis of the newborn (SCFN) is a very rare disorder, which can be complicated by hypercalcaemia and thrombocytopenia. The case is presented of an infant with SCFN and symptomatic hypercalcaemia, who developed calcifications in the liver, the inferior vena cava, and the atrial septum of the heart. The hypercalcaemia was treated with hyperhydration, frusemide, glucocorticoids, and a diet low in calcium and vitamin D. Clinical features, diagnosis, complications, and treatment of this rare condition are discussed.

  • subcutaneous fat necrosis of the newborn
  • hypercalcaemia
  • calcifications
  • thrombocytopenia

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