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Dose regimen for vancomycin not needing serum peak levels?
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  • Published on: 9 January 2022
    Authors reply to Dr Sunil's letter

    Dear Editor

    We are grateful to Dr Sunil for highlighting the issue of concommitent aminogycoside use with vancomycin. We agree that sick preterms are different and that it would be imprudent to abandon measuring vancomycin serum levels altogether. However, we do not change our recommendation that trough levels are sufficient in most cases. We are not aware of any data showing that concommitent use of aminoglycosi...

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    Conflict of Interest:
    None declared.
  • Published on: 9 January 2022
    Role of serum peak levels of vancomycin in NICUs

    Dear Editor

    The purpose of measuring serum levels of a drug is either to monitor the toxicity of the drug or the therapeutic concentration for a particular condition. Emergence of infections with beta-lactam-resistant Staphylococcus epidermidis, Staphylococcus aureus, and Enterococcus sp. has led to the frequent use of vancomycin in neonates. Vancomycin historically has had a reputation for tox...

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    Conflict of Interest:
    None declared.