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Posthaemorrhagic ventricular dilatation

Abstract

Posthaemorrhagic ventricular dilatation is the most serious direct complication of intraventricular haemorrhage after preterm birth. It results initially from multiple small blood clots throughout the cerebrospinal fluid channels impeding circulation and reabsorption. Management is difficult and new treatment approaches are needed.

  • preterm
  • intraventricular haemorrhage
  • hydrocephalus
  • transforming growth factor β
  • tissue plasminogen activator
  • IVH, intraventricular haemorrhage
  • PHVD, posthaemorrhagic ventricular dilatation
  • CSF, cerebrospinal fluid
  • TGFβ1, transforming growth factor β1

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