Editor—Recently, Miallet al 1 have reported a rapid rise in serum creatinine in the first 48 hours of life in neonates. But we have noticed in our clinical day to day practice that this rise is transient and may not be clinically significant. To confirm this, we looked at the initial serum creatinine levels on a stable group of term neonates admitted to the neonatal intensive care of King Fahd Hospital of the University, Al-Khobar, Saudi Arabia.

Neonates with congenital anomalies, perinatal asphyxia, and those requiring ventilatory support were excluded. The serum creatinine levels were measured together with electrolytes …