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Respiratory distress syndrome and antenatal corticosteroid treatment in premature twins
  1. DOUG HACKING,
  2. ANDREW WATKINS,
  3. SIMON FRASER
  1. Department of Paediatrics, Mercy Hospital for Women
  2. Clarendon Street, East Melbourne
  3. Victoria 3002, Australia
  4. Clinical Epidemiology and Biostatistics Unit
  5. Murdoch Children's Research Institute, Royal Children's Hospital and
  6. Department of Paediatrics, University of Melbourne
  7. Melbourne, Victoria 3052, Australia
    1. RORY WOLFE,
    2. TERRY NOLAN
    1. Department of Paediatrics, Mercy Hospital for Women
    2. Clarendon Street, East Melbourne
    3. Victoria 3002, Australia
    4. Clinical Epidemiology and Biostatistics Unit
    5. Murdoch Children's Research Institute, Royal Children's Hospital and
    6. Department of Paediatrics, University of Melbourne
    7. Melbourne, Victoria 3052, Australia

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      Editor—Randomised, placebo controlled trials of antenatal corticosteroid administration have not shown a significant reduction in the incidence of respiratory distress syndrome (RDS) in premature twins.1 Subsequent retrospective studies examining the effect of steroids on twin pregnancies have shown conflicting results.2 3

      Further to our recent article,4 we have investigated the relation between respiratory distress and antenatal corticosteroid treatment in premature twins from the same historical cohort selected …

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