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Neonatal paroxetine withdrawal syndrome
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  • Published on:
    Neonatal paroxetine withdrawal syndrome or actually serotonin syndrome? - Authors' response

    Dear Editor,

    Isbister and colleagues point out important issues in defining the syndrome we and others described.[1][2] Their argument is that the described syndrome is due to a hyper-serotonergic state, rather than a lack of serotonin effect, as the term "withdrawal" suggests. We agree that this issue must be clearly solved because of the significant implications in the clinical management of some of the patient...

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    Conflict of Interest:
    None declared.
  • Published on:
    Neonatal paroxetine withdrawal syndrome or actually serotonin syndrome?
    Dear Editor

    We would like to comment on the article “Neonatal paroxetine withdrawal syndrome” in the March 2001 issue of the journal.[1] The authors describe what they have called “neonatal paroxetine withdrawal syndrome”. However the syndrome reported in the 4 neonates appears to be more consistent with serotonin toxicity, rather than withdrawal of paroxetine.

    The literature to date contains one large serie...

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    Conflict of Interest:
    None declared.