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Withdrawal reactions of a premature neonate after maternal use of paroxetine
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  1. I J M NIJHUIS,
  2. G W M KOK-VAN ROOIJ,
  3. A N BOSSCHAART
  1. Medisch Spectrum Twente, Department of Paediatrics
  2. PO Box 50.000, 7500 KA, Enschede
  3. The Netherlands
  4. IlseNijhuis@cs.com

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    Editor—Paroxetine is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) group. Its use during pregnancy can lead to premature birth and neonatal withdrawal symptoms.

    A girl was born after 35+2 weeks gestation (birth weight 2690 g) and admitted because of prematurity. The pregnancy and delivery had been uneventful (Apgar score 9/10/10), with no apparent reason for prematurity. There were no problems in the first few days and she drank quickly (bottle feeding).

    Thereafter she …

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