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Importance of intestinal colonisation in the maturation of humoral immunity in early infancy: a prospective follow up study of healthy infants aged 0–6 months
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  • Published on:
    Early mucosal immunocompetence in infancy
    • BM Seidel, Division of Paediatric Immunology
    • Other Contributors:
      • S Schubert

    Dear Editor,

    The study of Groenland et al contributes remarkably to the understanding of the role of intenstinal colonisation and the maturation of the mucosal immune system.

    However, with reference to reports of MacDonald,[1] Savilahti,[2] and Burgio et al,[3] they suggest that the mucosal immune system with its predominant secretory IgA is quantitatively and functionally defective for a variable peri...

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    Conflict of Interest:
    None declared.