Editor—Maternal clomipramine use during pregnancy may cause epilepsy in newborns.1-3 We present the case of a neonate who developed a thus far unrecognised manifestation of clomipramine withdrawal.

A 38 year old woman had been treated for depression throughout pregnancy with clomipramine (100 mg/day). No other medication had been taken. A boy weighing 3370 g was born at term; he had excellent Apgar scores. Two days later, the child was jittery following startling impulses. On the fifth day, simultaneous …